Nishino Shrine enshrines three deities: Toyotama-hime, Ugayafukiaezu no mikoto, and Emperor Ōjin (venerated as Hondawake no mikoto). The shrine is particularly known for granting blessings related to safe childbirth, fertility, matchmaking, and marital harmony. Many visitors come specifically to pray at the stone statues of parent and child dogs, which are revered as symbols of safe childbirth.