The museum displays artifacts and exhibits covering the history of Tsuyama and the Mimasaka region from ancient times to the modern era. Key collections include materials related to Tsuyama Castle and the Matsudaira clan, exhibits on Rangaku (Dutch Learning) showing Tsuyama's role in absorbing Western knowledge during the Edo period, and displays of local crafts, tools, and everyday items from the castle town era. Scale models, historical documents, and rotating special exhibitions provide comprehensive insights into the region's cultural development.