Harajuku is Tokyo's most famous fashion and youth culture district, located in Shibuya Ward between Shinjuku to the northwest and Shibuya to the south. It usually suits travelers who want a well-connected city base with a clear neighborhood identity rather than a purely sightseeing-only stop.
Yes, Harajuku is a good place to stay in Tokyo if you want a well-connected base with restaurants, transit, and straightforward access to the rest of Tokyo. It is less ideal if you want the city's busiest sightseeing streets directly outside your hotel from morning to night.
Harajuku works well across both day and evening, but the atmosphere changes by hour. Daytime is better for cafés, shrines, shops, or nearby landmarks, while the evening is when the area's dining and neighborhood atmosphere become more noticeable.
Harajuku pairs well with Shibuya and Shinjuku. It is easy to combine with another central district because you can use it as either a meal stop, a short neighborhood walk, or part of a wider day built around transit.